Cisplatin and cerebral infarction Introduction Cisplatin (Platosin) is indicated for the treatment of extensive or metastatic tumours: testicular carcinoma (palliative and curative therapy), ovarian carcinoma (stage III and IV) and squamous cell carcinoma of the head and neck (palliative
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چکیده
Until December 8, 2007, the Netherlands Pharmacovigilance Centre Lareb received 12 reports of (specific symptoms of) cerebral infarction associated with the use of cisplatin. Reported terms were brainstem infarction, arterial thromboembolism, cerebral infarction, cerebrovascular accident, cerebrovascular disorder, embolism, hemiplegia, paralysis, and cortical blindness. Four of these reports were excluded because of lack of precise information on cerebral infarction or causality was not likely according to Lareb.
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